Prevalence and genotype distribution of hepatitis C virus in Mongolia: Systematic review and meta-analysis

ObjectiveTo characterize hepatitis C virus (HCV) infection epidemiology in Mongolia.MethodPublications on HCV antibody (Ab) and RNA prevalence, and/or genotypes/subtypes were systematically reviewed reported following PRISMA guidelines. Random-effects meta-analyses age adjustments conducted to estimate the prevalence of Mongolians exposed (pooled HCV-Ab prevalence) by time period, sex, at-risk populations; chronically-infected individuals.ResultsThe national pooled was 12.3% 2000–2009 11.2% 2013. Sex-specific appeared higher among females than males (14.0% versus 6.8%). Age-specific significantly increased from 3.7% children (aged 0–10 years) 34.1% people aged ?50 years (p < 0.001). Among adult general population (low-risk population), age-adjusted 8.1%. Age-adjusted chronic adults 6.0%. healthcare workers, 18.0%. patients with liver diseases, 53.7%. individuals engaging risky sexual behaviors, 11.1%. The identified circulating 1b (58.0%), 2a (21.7%), 1a (20.2%).ConclusionThe Mongolia be highest worldwide. Higher clinical setting indicated potential ongoing iatrogenic occupational transmission. Additionally, transmission community settings should investigated.